Self-Emulsifying Drug Delivery Systems: A Review
نویسندگان
چکیده
منابع مشابه
Recent advances in self emulsifying drug delivery system - A review
Self-emulsifying drug delivery systems (SEDDS) are usually used to improve the bioavailability of hydrophobic drugs. Approximately 40% of new chemical entities exhibit poor aqueous solubility and present a major challenge to modern drug delivery system, because of their low bioavailability. From time to time many workers have claimed various rational applications of Self-emulsifying formulation...
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More than 60% of drugs have lipophilic nature and exhibit poor water-solubility. The dissolution is the rate limiting step in their absorption and oral bioavailability. To overcome this problem one approach to enhance dissolution is Self-Dispersing Lipid Formulations (SDLFs). Generally, an emulsified dosage form is rapidly absorbable; therefore, it makes sure that a poorly water-soluble drug is...
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Volume 5 • Issue 3 • 1000130 J Adv Chem Eng ISSN: 2090-4568 ACE an open access journal Self-Emulsifying Drug Delivery Systems (SEDDS) in Pharmaceutical Development Beatriz Zanchetta1,2, Marco Vinícius Chaud3 and Maria Helena Andrade Santana1,* 1Department of Engineering of Materials and Bioprocesses, School of Chemical Engineering, University of Campinas, SP, Brazil 2Department of Research and ...
متن کاملMucus permeating thiolated self-emulsifying drug delivery systems.
CONTEXT Mucus represents a critical obstacle for self-emulsifying drug delivery systems (SEDDS) targeting the epithelial membrane site. OBJECTIVE The aim of the study was the development of a novel SEDDS to overcome the mucus barrier. MATERIALS AND METHODS Two novel conjugates N-dodecyl-4-mercaptobutanimidamide (thiobutylamidine-dodecylamine, TBA-D) and 2-mercapto-N-octylacetamide (thioglyc...
متن کاملSelf Micro Emulsifying Drug Delivery System - A Capsulization
The aim of the present work is to emphasize about the importance and to make a capsule review on self micro emulsifying drug delivery system. Oral route of drug administration has been the most prominent way of drug delivery system, because of its ability to prepare the formulation in an economical way, easy to administer, does not require any specific storage condition compared with parenteral...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutical and Life Sciences
سال: 2013
ISSN: 2305-0330
DOI: 10.3329/ijpls.v2i2.15453